According to the FHP, Vasquez ran a stop sign at the intersection of Aurora Road and Turtle Mound Road, causing the Ford to strike the rear of the Toyota.
The Ford then continued westbound and struck a 2014 Jeep driven by 80-year-old David Katz.
A 34-year-old male passenger in the Ford, Ricardo Guadelupe, died at the scene.
Vasquez is in critical condition and was transported to Holmes Regional Medical Center.
Watkins and Katz suffered minor injuries.
Everyone involved in the crash are from Melbourne, Florida.